A concept is a general notion or construct of something that doesn’t necessarily need all the pieces exactly and depends on context. How does the…
Lab Talk
Measuring a Thought
We all intuitively recognize a thought when we have one but a thought is hard to describe as measurable or observable factors. We all have…
Transport of Proteins, RNA and DNA among Brain Cells
The discoveries of exosomes and tunneling nanotubes that allow intercellular transport of proteins, RNA and DNA among neurons and glia change how we think about…
Two Successful Theories in Biology
The theory of evolution and the Hodgkin-Huxley model of the action potential are two successful theories in biology that are relevant to the brain. Why…
Constructing a Theory of the Brain
What are the necessary elements for a genuine theory of the brain and what will it take to construct one? In my previous posts I…
Individual Variability in Adolescent Brain and Behavior
Little is known about the developmental trajectory of the brain through adolescence but a few studies suggest there is large inter-person variability and differences that…
Engineering a Brain: Can This Work?
Many theoretical proposals in neuroscience are presented in the form of an engineering solution. But engineering a solution is a different process than creating a…
EEG Connectivity Using Phase Lag Index
Phase Lag Index is a tool to estimate connectivity in EEG in a way that eliminates volume conduction effects. However, it is also likely to…
Building The Brain With Modules
Models in computational neuroscience that solve for one outcome cannot combine with one that solves for another. Can a modular approach solve this? The short…
The Crisis of Computational Neuroscience
Computational Models attempt to explain the behavior of the brain using neural network simulations, but assumptions that help simulate one phenomenon are destructive to the…